The average bus between Saint Cloud and Key West takes 18h 11m and the fastest bus takes 15h 54m. The bus service runs several times per day from Saint Cloud to Key West. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Saint Cloud and Key West. The earliest departure is at 1:17 PM in the afternoon, and the last departure from Saint Cloud is at 10:07 PM which arrives into Key West at 3:42 PM. All services require a transfer at Pleasant St & Neptune Rd and take an average of 18h 11m. The schedules shown below are for the next available departures.
Arrives next day




22h 13m • 4 changes
Arrives next day




18h 34m • 4 changes
Arrives next day




23h 44m • 4 changes
Arrives next day




18h 34m • 4 changes
Arrives next day




15h 54m • 4 changes
Arrives next day




17h 39m • 4 changes
Arrives next day




15h 54m • 4 changes
Arrives next day




17h 39m • 4 changes
Want to know about travelling from Saint Cloud to Key West? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Saint Cloud to Key West. However, there are services departing from Saint Cloud station and arriving at Key West station via Miami Airport Station station. The journey, including transfers, takes approximately 18h 11m.
Saint Cloud to Key West bus services, operated by Lynx Central Florida Transport, depart from Orlando station.
Saint Cloud to Key West bus services, operated by Lynx Central Florida Transport, arrive at N Roosevelt & 3rd Street station.
The distance between Saint Cloud and Key West is 413.7 km. The road distance is 659 km.
You can take a bus from E Us 192 & Ohio Ave to N Roosevelt & 3rd Street via Pleasant St & Neptune Rd, Florida Mall, Orlando, Miami Airport Station, Big Pine Key, and Big Pine Key - CVS / MM30 in around 14h 3m.