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Saint Louis County to Chicago buses

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Trip Overview

The average bus between Saint Louis County and Chicago takes 8h 27m and the fastest bus takes 7h 59m. The bus service runs several times per day from Saint Louis County to Chicago. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

8h 27m
Duration
338 mi
Distance
$62
Average price
3 times a day
Frequency

Bus (Flixbus)

best
  1. Take the bus from St Louis Bus Station to Chicago Bus Stationbus bus FlixBus N2521 / ...
8h 52m
$52–87

Saint Louis County to Chicago bus times

Buses run 3 times a day between Saint Louis County and Chicago. The earliest departure is at 7:33 AM in the morning, and the last departure from Saint Louis County is at 9:36 PM which arrives into Chicago at 5:35 AM. All services require a transfer at Clayton Transit Center and take an average of 8h 27m. The schedules shown below are for the next available departures.

Frequently asked questions

Want to know about travelling from Saint Louis County to Chicago? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Saint Louis County to Chicago.ExpandLaunch map view
  • Distance: 338.3 mi
  • Duration: 8h 27m

What companies run services between Saint Louis County, MO, USA and Chicago, IL, USA?

Flixbus USA operates a bus from St Louis Bus Station to Chicago Bus Station 4 times a day. Tickets cost $50–85 and the journey takes 6h 5m.

Operators