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Salem to St. Louis buses

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Trip Overview

The bus between Salem and St. Louis takes 46h 15m. The bus runs, on average, 6 times per week from Salem to St. Louis. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

46h 15m
Duration
2,274 mi
Distance
$489
Average price
6 times a week
Frequency

Salem to St. Louis bus times

Buses run 6 times a week between Salem and St. Louis. The service departs Salem at 7:55 AM in the morning, which arrives into St. Louis at 08:10:00. All services require a transfer at Pasco Bus Stop and take an average of 46h 15m. The schedules shown below are for the next available departures.

Departing Wednesday, November 4, 2026

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    Arrives +2 days

    Flixbus USAGreyhound USAGreyhound USA46h 15m • 2 changes

Departing Thursday, November 5, 2026

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    Arrives +2 days

    Flixbus USAGreyhound USAGreyhound USA46h 15m • 2 changes

Departing Friday, November 6, 2026

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    Arrives +2 days

    Flixbus USAGreyhound USAGreyhound USA46h 15m • 2 changes

Departing Saturday, November 7, 2026

  •  → 

    Arrives +2 days

    Flixbus USAGreyhound USAGreyhound USA46h 15m • 2 changes

Departing Sunday, November 8, 2026

  •  → 

    Arrives +2 days

    Flixbus USAGreyhound USAGreyhound USA46h 15m • 2 changes

Departing Monday, November 9, 2026

  •  → 

    Arrives +2 days

    Flixbus USAGreyhound USAGreyhound USA46h 15m • 2 changes

Frequently asked questions

Want to know about travelling from Salem to St. Louis? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Salem to St. Louis.ExpandLaunch map view
  • Distance: 2,273.8 mi
  • Duration: 46h 15m

What companies run services between Salem, OR, USA and St. Louis, MO, USA?

You can take a bus from Salem to St Louis Bus Station via Pasco Bus Stop and Denver Union Station in around 46h 45m.

Operators