Rome2Rio

Salisbury to Chicago buses

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Trip Overview

The average bus between Salisbury and Chicago takes 25h 33m and the fastest bus takes 23h 40m. The bus service runs several times per day from Salisbury to Chicago. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

25h 33m
Duration
863 mi
Distance
$274
Average price
Twice daily
Frequency

Salisbury to Chicago bus times

Buses run twice daily between Salisbury and Chicago. The earliest departure is at 11:20 AM in the morning, and the last departure from Salisbury is at 5:20 PM which arrives into Chicago at 8:05 PM. All services require a transfer, and take on average 25h 33m. The schedules shown below are for the next available departures.

Departing Wednesday, November 11, 2026

  •  → 

    Arrives next day

    BayRunner ShuttleGreyhound USA23h 40m • 1 change
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    Arrives next day

    BayRunner ShuttleGreyhound USA27h 45m • 1 change

Departing Thursday, November 12, 2026

  •  → 

    Arrives next day

    BayRunner ShuttleGreyhound USA23h 40m • 1 change
  •  → 

    Arrives next day

    BayRunner ShuttleGreyhound USA27h 45m • 1 change

Departing Friday, November 13, 2026

  •  → 

    Arrives next day

    BayRunner ShuttleGreyhound USA23h 40m • 1 change
  •  → 

    Arrives next day

    BayRunner ShuttleGreyhound USA27h 45m • 1 change

Departing Saturday, November 14, 2026

  •  → 

    Arrives next day

    BayRunner ShuttleGreyhound USA23h 40m • 1 change
  •  → 

    Arrives next day

    BayRunner ShuttleGreyhound USA27h 45m • 1 change

Departing Sunday, November 15, 2026

  •  → 

    Arrives next day

    BayRunner ShuttleGreyhound USA23h 40m • 1 change
  •  → 

    Arrives next day

    BayRunner ShuttleGreyhound USA27h 45m • 1 change

Departing Monday, November 16, 2026

  •  → 

    Arrives next day

    BayRunner ShuttleGreyhound USA23h 40m • 1 change
  •  → 

    Arrives next day

    BayRunner ShuttleGreyhound USA27h 45m • 1 change

Departing Tuesday, November 17, 2026

  •  → 

    Arrives next day

    BayRunner ShuttleGreyhound USA23h 40m • 1 change

Frequently asked questions

Want to know about travelling from Salisbury to Chicago? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Salisbury to Chicago.ExpandLaunch map view
  • Distance: 863.1 mi
  • Duration: 25h 33m

What companies run services between Salisbury, MD, USA and Chicago, IL, USA?

You can take a bus from Salisbury to Chicago Bus Station via Baltimore Downtown Bus Station in around 22h 20m.

Operators