The average bus between Salisbury and Durham takes 12h 15m and the fastest bus takes 10h 30m. The bus service runs several times per day from Salisbury to Durham. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Salisbury and Durham. The earliest departure is at 11:20 AM in the morning, and the last departure from Salisbury is at 5:20 PM which arrives into Durham at 3:50 AM. All services require a transfer at Baltimore, MD - Greyhound Bus Terminal Downtown and take an average of 12h 15m. The schedules shown below are for the next available departures.
Arrives next day

13h 45m • 1 change
Arrives next day

10h 30m • 1 change
Arrives next day

13h 45m • 1 change
Arrives next day

10h 30m • 1 change
Arrives next day

13h 45m • 1 change
Arrives next day

10h 30m • 1 change
Arrives next day

13h 45m • 1 change
Arrives next day

10h 30m • 1 change
Want to know about travelling from Salisbury to Durham? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Salisbury to Durham. However, there are services departing from Salisbury station and arriving at Durham station via Baltimore, MD - Greyhound Bus Terminal Downtown. The journey, including transfers, takes approximately 12h 15m.
Salisbury to Durham bus services, operated by BayRunner Shuttle, depart from Salisbury, MD station.
Salisbury to Durham bus services, operated by BayRunner Shuttle, arrive at Durham station.
Book your Salisbury to Durham bus tickets online with BayRunner Shuttle, Flixbus USA and Greyhound USA.
The distance between Salisbury and Durham is 393.3 km. The road distance is 699 km.
You can take a bus from Salisbury, MD to Durham via Baltimore, MD - Greyhound Bus Terminal Downtown and Baltimore Downtown Bus Station in around 11h 35m.