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Salisbury to Durham buses

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Trip Overview

The average bus between Salisbury and Durham takes 12h 37m and the fastest bus takes 10h 30m. The bus service runs several times per day from Salisbury to Durham. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

12h 37m
Duration
435 mi
Distance
$184
Average price
Twice daily
Frequency

Salisbury to Durham bus times

Buses run twice daily between Salisbury and Durham. The earliest departure is at 11:20 AM in the morning, and the last departure from Salisbury is at 5:20 PM which arrives into Durham at 3:50 AM. All services require a transfer, and take on average 12h 37m. The schedules shown below are for the next available departures.

Departing Friday, November 6, 2026

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    Arrives next day

    BayRunner ShuttleGreyhound USA14h 10m • 1 change
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    Arrives next day

    BayRunner ShuttleFlixbus USA10h 30m • 1 change

Departing Saturday, November 7, 2026

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    Arrives next day

    BayRunner ShuttleGreyhound USA14h 10m • 1 change
  •  → 

    Arrives next day

    BayRunner ShuttleFlixbus USA10h 30m • 1 change

Departing Sunday, November 8, 2026

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    Arrives next day

    BayRunner ShuttleGreyhound USA14h 10m • 1 change
  •  → 

    Arrives next day

    BayRunner ShuttleFlixbus USA10h 30m • 1 change

Departing Monday, November 9, 2026

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    Arrives next day

    BayRunner ShuttleGreyhound USA14h 10m • 1 change
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    Arrives next day

    BayRunner ShuttleGreyhound USA11h 30m • 1 change

Departing Tuesday, November 10, 2026

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    Arrives next day

    BayRunner ShuttleGreyhound USA14h 10m • 1 change
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    Arrives next day

    BayRunner ShuttleGreyhound USA11h 30m • 1 change

Departing Wednesday, November 11, 2026

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    Arrives next day

    BayRunner ShuttleGreyhound USA14h 10m • 1 change
  •  → 

    Arrives next day

    BayRunner ShuttleFlixbus USA10h 30m • 1 change

Departing Thursday, November 12, 2026

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    Arrives next day

    BayRunner ShuttleGreyhound USA14h 10m • 1 change

Frequently asked questions

Want to know about travelling from Salisbury to Durham? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Salisbury to Durham.ExpandLaunch map view
  • Distance: 434.8 mi
  • Duration: 12h 37m

What companies run services between Salisbury, MD, USA and Durham, NC, USA?

You can take a bus from Salisbury to Durham via Baltimore Downtown Bus Station in around 11h 35m.

Operators