The average bus between Salisbury and Frederick takes 5h and the fastest bus takes 4h 50m. The bus service runs several times per day from Salisbury to Frederick. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 4 times a day between Salisbury and Frederick. The earliest departure is at 7:20 AM in the morning, and the last departure from Salisbury is at 5:20 PM which arrives into Frederick at 10:10 PM. All services require a transfer, and take on average 5h. The schedules shown below are for the next available departures.

5h 10m • 1 change

4h 50m • 1 change

5h 10m • 1 change

4h 50m • 1 change

5h 10m • 1 change

4h 50m • 1 change

5h 10m • 1 change

4h 50m • 1 change

5h 10m • 1 change

4h 50m • 1 change

5h 10m • 1 change

4h 50m • 1 change
Want to know about travelling from Salisbury to Frederick? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Salisbury to Frederick. However, there are services departing from Salisbury station and arriving at Frederick station via BWI Amtrak Station station. The journey, including transfers, takes approximately 5h.
Salisbury to Frederick bus services, operated by BayRunner Shuttle, depart from Salisbury, MD station.
Salisbury to Frederick bus services, operated by BayRunner Shuttle, arrive at Frederick Transit Center station.
Book your Salisbury to Frederick bus tickets online with BayRunner Shuttle.
The distance between Salisbury and Frederick is 195.7 km. The road distance is 248 km.
You can take a bus from Salisbury, MD to Frederick Transit Center via BWI Amtrak Station in around 4h 20m.