The average bus between Salzburg and Prague takes 6h 31m and the fastest bus takes 6h 2m. The bus service runs several times per day from Salzburg to Prague. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 4 times a day between Salzburg and Prague. The earliest departure is at 6:36 AM in the morning, and the last departure from Salzburg is at 11:42 PM which arrives into Prague at 5:45 AM. All services require a transfer at Salzburg Alpensiedlung P+R and take an average of 6h 31m. The schedules shown below are for the next available departures.

6h 55m • 1 change

6h 45m • 1 change

6h 20m • 1 change
Arrives next day

6h 2m • 1 change

6h 55m • 1 change

6h 45m • 1 change

6h 20m • 1 change
Arrives next day

6h 2m • 1 change

7h • 1 change

6h 45m • 1 change

6h 14m • 1 change
Arrives next day

6h 2m • 1 change

7h 19m • 1 change

6h 44m • 1 change

6h 20m • 1 change
Arrives next day

6h 2m • 1 change
Want to know about travelling from Salzburg to Prague? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Salzburg to Prague. However, there are services departing from Salzburg station and arriving at Prague station via Praha, ÚAN Florenc. The journey, including transfers, takes approximately 6h 31m.
Salzburg to Prague bus services, operated by Salzburg Verkehr Gmbh, depart from Salzburg South station.
Salzburg to Prague bus services, operated by Salzburg Verkehr Gmbh, arrive at Praha, ÚAN Florenc station.
The distance between Salzburg and Prague is 309.2 km. The road distance is 388 km.
FlixBus operates a bus from Salzburg South to Praha, ÚAN Florenc 4 times a day. Tickets cost Kč 800–1,400 and the journey takes 5h 55m.