The average bus between San Antonio and Charleston takes 37h 27m and the fastest bus takes 36h 10m. The bus service runs several times per day from San Antonio to Charleston. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between San Antonio and Charleston. The earliest departure is at 7:35 AM in the morning, and the last departure from San Antonio is at 7:15 PM which arrives into Charleston at 8:25 AM. All services require a transfer at Houston Bus Station and take an average of 37h 27m. The schedules shown below are for the next available departures.
Arrives next day



39h 45m • 3 changes
Arrives +2 days



37h 10m • 3 changes
Arrives next day



39h 45m • 3 changes
Arrives +2 days



37h 10m • 3 changes
Arrives next day



39h 45m • 3 changes
Arrives +2 days



37h 10m • 3 changes
Arrives next day



39h 45m • 3 changes
Arrives +2 days



37h 10m • 3 changes
Want to know about travelling from San Antonio to Charleston? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from San Antonio to Charleston. However, there are services departing from San Antonio station and arriving at Charleston station via Houston Bus Station station. The journey, including transfers, takes approximately 37h 27m.
San Antonio to Charleston bus services, operated by Greyhound USA, depart from San Antonio Bus Station.
San Antonio to Charleston bus services, operated by Greyhound USA, arrive at Charleston, WV station.
Book your San Antonio to Charleston bus tickets online with Greyhound USA, Barons Bus and Flixbus USA.
The distance between San Antonio and Charleston is 1,841.3 km. The road distance is 2,516 km.
You can take a bus from San Antonio Bus Station to Charleston, WV via Houston Bus Station, Atlanta Bus Station, and Charlotte Bus Station in around 32h 15m.