The average bus between San Antonio and Des Moines takes 45h 30m and the fastest bus takes 43h 35m. The bus runs, on average, 4 times per week from San Antonio to Des Moines. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 4 times a week between San Antonio and Des Moines. The earliest departure is at 7:30 AM in the morning, and the last departure from San Antonio is at 7:30 AM which arrives into Des Moines at 11:45 AM. All services require a transfer at Denton and take an average of 45h 30m. The schedules shown below are for the next available departures.
Want to know about travelling from San Antonio to Des Moines? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from San Antonio to Des Moines. However, there are services departing from San Antonio station and arriving at Des Moines station via Denton. The journey, including transfers, takes approximately 45h 30m.
San Antonio to Des Moines bus services, operated by Flixbus USA, depart from San Antonio Bus Station.
San Antonio to Des Moines bus services, operated by Flixbus USA, arrive at Des Moines station.
Book your San Antonio to Des Moines bus tickets online with Flixbus USA and Jefferson Lines.
The distance between San Antonio and Des Moines is 1,423.6 km. The road distance is 1,687 km.
You can take a bus from San Antonio Bus Station to Des Moines via Denton, Kansas City Bus Station, and Kansas City in around 22h.
