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San Antonio to Frederick buses

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Trip Overview

The average bus between San Antonio and Frederick takes 41h 40m and the fastest bus takes 41h 25m. The bus service runs several times per day from San Antonio to Frederick. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

41h 40m
Duration
1,721 mi
Distance
$373
Average price
Twice daily
Frequency

San Antonio to Frederick bus times

Buses run twice daily between San Antonio and Frederick. The earliest departure is at 1:05 AM at night, and the last departure from San Antonio is at 1:30 PM which arrives into Frederick at 8:30 AM. All services require a transfer at Houston Bus Station and take an average of 41h 40m. The schedules shown below are for the next available departures.

Departing Tuesday, November 10, 2026

  •  → 

    Arrives +2 days

    Greyhound USAGreyhound USAFlixbus USAGreyhound USA42h • 3 changes

Departing Wednesday, November 11, 2026

  •  → 

    Arrives next day

    Greyhound USAGreyhound USAGreyhound USAGreyhound USA41h 25m • 3 changes
  •  → 

    Arrives +2 days

    Greyhound USAGreyhound USAFlixbus USAGreyhound USA42h • 3 changes

Departing Thursday, November 12, 2026

  •  → 

    Arrives next day

    Greyhound USAGreyhound USAGreyhound USAGreyhound USA41h 25m • 3 changes
  •  → 

    Arrives +2 days

    Greyhound USAGreyhound USAFlixbus USAGreyhound USA42h • 3 changes

Departing Friday, November 13, 2026

  •  → 

    Arrives next day

    Greyhound USAGreyhound USAGreyhound USAGreyhound USA41h 25m • 3 changes
  •  → 

    Arrives +2 days

    Greyhound USAGreyhound USAFlixbus USAGreyhound USA42h • 3 changes

Departing Saturday, November 14, 2026

  •  → 

    Arrives next day

    Greyhound USAGreyhound USAGreyhound USAGreyhound USA41h 25m • 3 changes
  •  → 

    Arrives +2 days

    Greyhound USAGreyhound USAFlixbus USAGreyhound USA42h • 3 changes

Departing Sunday, November 15, 2026

  •  → 

    Arrives next day

    Greyhound USAGreyhound USAGreyhound USAGreyhound USA41h 25m • 3 changes

Frequently asked questions

Want to know about travelling from San Antonio to Frederick? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from San Antonio to Frederick.ExpandLaunch map view
  • Distance: 1,721 mi
  • Duration: 41h 40m

What companies run services between San Antonio, TX, USA and Frederick, MD, USA?

You can take a bus from San Antonio Bus Station to Frederick Bus Station via Houston Bus Station, Atlanta Bus Station, and Washington Union Station in around 36h 10m.

Operators