The average bus between San Antonio and Tyler takes 8h 22m and the fastest bus takes 7h 50m. The bus service runs several times per day from San Antonio to Tyler. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between San Antonio and Tyler. The earliest departure is at 1:30 AM at night, and the last departure from San Antonio is at 9:55 PM which arrives into Tyler at 5:45 AM. All services require a transfer, and take on average 8h 22m. The schedules shown below are for the next available departures.

7h 55m • 1 change
9h 6m • 1 changeArrives next day

8h 45m • 1 change
7h 55m • 1 change
9h 6m • 1 changeArrives next day

7h 50m • 1 change
7h 55m • 1 change
9h 6m • 1 changeArrives next day

7h 50m • 1 change
7h 55m • 1 change
9h 6m • 1 changeArrives next day

7h 50m • 1 changeWant to know about travelling from San Antonio to Tyler? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from San Antonio to Tyler. However, there are services departing from San Antonio station and arriving at Tyler station via Dallas Bus Station station. The journey, including transfers, takes approximately 8h 22m.
San Antonio to Tyler bus services, operated by Greyhound USA, depart from San Antonio Bus Station.
San Antonio to Tyler bus services, operated by Greyhound USA, arrive at Tyler station.
Book your San Antonio to Tyler bus tickets online with Greyhound USA and Flixbus USA.
The distance between San Antonio and Tyler is 445.8 km. The road distance is 622 km.
You can take a bus from San Antonio Bus Station to Tyler via Dallas Bus Station in around 7h 45m.