The average bus between San Clemente and Santa Ana takes 1h 59m and the fastest bus takes 1h 37m. There is an hourly bus service from San Clemente to Santa Ana. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run hourly between San Clemente and Santa Ana. The earliest departure is at 5:12 AM in the morning, and the last departure from San Clemente is at 9:17 PM which arrives into Santa Ana at 11:24 PM. All services require a transfer, and take on average 1h 59m. The schedules shown below are for the next available departures.

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1h 50m • 1 changeWant to know about travelling from San Clemente to Santa Ana? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from San Clemente to Santa Ana. However, there are services departing from Calle De Los Molinos-Avd Pico station and arriving at Civic Center-Main station via Laguna Hills Trans Ctr Dock 7 station. The journey, including transfers, takes approximately 1h 59m.
San Clemente to Santa Ana bus services, operated by OCTA, depart from Calle De Los Molinos-Avd Pico station.
San Clemente to Santa Ana bus services, operated by OCTA, arrive at Civic Center-Main station.
Book your San Clemente to Santa Ana bus tickets online with Omio.
The distance between San Clemente and Santa Ana is 42.6 km. The road distance is 49 km.
You can take a bus from Calle De Los Molinos-Avd Pico to Civic Center-Main via Laguna Hills Trans Ctr Dock 5 in around 2h 5m.