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San Diego to Guelph buses

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Trip Overview

The bus between San Diego and Guelph takes 4d 8h. The bus runs, on average, 3 times per week from San Diego to Guelph. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

4d 8h
Duration
4,441 km
Distance
$786
Average price
3 times a week
Frequency

San Diego to Guelph bus times

Buses run 3 times a week between San Diego and Guelph. The service departs San Diego at 10:15 PM at night, which arrives into Guelph at 09:40:00. All services require a transfer at Los Angeles Union Station and take an average of 4d 8h. The schedules shown below are for the next available departures.

Departing Wednesday, October 21, 2026

  •  → 

    Arrives +5 days

    Flixbus USAGreyhound USAGreyhound USAGreyhound USAFlixbus USAFlixbus USA4d 8h • 5 changes

Departing Thursday, October 22, 2026

  •  → 

    Arrives +5 days

    Flixbus USAGreyhound USAGreyhound USAGreyhound USAFlixbus USAFlixbus USA4d 8h • 5 changes

Frequently asked questions

Want to know about travelling from San Diego to Guelph? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from San Diego to Guelph.ExpandLaunch map view
  • Distance: 4,441.5 km
  • Duration: 4d 8h

What companies run services between San Diego, CA, USA and Guelph, ON, Canada?

You can take a bus from San Diego to Guelph via Los Angeles Union Station, St Louis Bus Station, Indianapolis Union Station, Detroit Bus Station, and Kitchener in around 2d 15h.

Operators