The average bus between San Diego and Irwindale takes 6h 40m and the fastest bus takes 4h 21m. The bus service runs several times per day from San Diego to Irwindale. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between San Diego and Irwindale. The earliest departure is at 7:00 AM in the morning, and the last departure from San Diego is at 7:25 PM which arrives into Irwindale at 5:56 AM. All services require a transfer at Los Angeles Union Station and take an average of 6h 40m. The schedules shown below are for the next available departures.


4h 50m • 2 changes


4h 24m • 2 changes
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10h 31m • 2 changes


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4h 24m • 2 changes
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10h 31m • 2 changes


4h 50m • 2 changes


4h 24m • 2 changes
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11h 40m • 2 changes


4h 41m • 2 changes


4h 21m • 2 changes
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11h 40m • 2 changes


4h 41m • 2 changes


4h 21m • 2 changes
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10h 31m • 2 changes
Want to know about travelling from San Diego to Irwindale? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from San Diego to Irwindale. However, there are services departing from San Diego station and arriving at Irwindale station via Los Angeles Union Station station. The journey, including transfers, takes approximately 6h 40m.
San Diego to Irwindale bus services, operated by Greyhound Mexico, depart from San Diego station.
San Diego to Irwindale bus services, operated by Greyhound Mexico, arrive at Los Angeles Union Station.
The distance between San Diego and Irwindale is 170.6 km. The road distance is 235 km.
Greyhound Mexico operates a bus from San Diego to Los Angeles Union Station 3 times a day. Tickets cost $23–40 and the journey takes 2h 55m.