The bus between San Diego and San Luis Obispo takes 17h 35m. The bus runs, on average, 4 times per week from San Diego to San Luis Obispo. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 4 times a week between San Diego and San Luis Obispo. The earliest departure is at 7:25 PM in the evening, and the last departure from San Diego is at 7:25 PM which arrives into San Luis Obispo at 1:00 PM. All services require a transfer, and take on average 17h 35m. The schedules shown below are for the next available departures.
Want to know about travelling from San Diego to San Luis Obispo? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from San Diego to San Luis Obispo. However, there are services departing from San Diego station and arriving at San Luis Obispo station via Los Angeles Union Station station. The journey, including transfers, takes approximately 17h 35m.
San Diego to San Luis Obispo bus services, operated by Greyhound Mexico, depart from San Diego station.
San Diego to San Luis Obispo bus services, operated by Greyhound Mexico, arrive at San Luis Obispo Railroad Museum station.
Book your San Diego to San Luis Obispo bus tickets online with Greyhound Mexico and Flixbus USA.
The distance between San Diego and San Luis Obispo is 430.6 km. The road distance is 508 km.
You can take a bus from San Diego to San Luis Obispo Railroad Museum via Los Angeles Union Station in around 7h 55m.
