- Distance: 90.5 mi
- Duration: 2h 5m
The average bus between San Diego and Santa Ana takes 2h 5m and the fastest bus takes 1h 55m. The bus service runs several times per day from San Diego to Santa Ana. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 5 times a day between San Diego and Santa Ana. The earliest departure is at 7:00 AM in the morning, and the last departure from San Diego is at 10:10 PM which arrives into Santa Ana at 12:15 AM. All services run direct with no transfers required, and take on average 2h 5m. The schedules shown below are for the next available departures.
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Want to know about travelling from San Diego to Santa Ana? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
Yes, there is a direct bus departing from San Diego station and arriving at Santa Ana station. Services depart 5 times a day, and operate Twice daily. The journey takes approximately 2h 5m.
San Diego to Santa Ana bus services, operated by Greyhound Mexico, depart from San Diego station.
San Diego to Santa Ana bus services, operated by Greyhound Mexico, arrive at Santa Ana station.
Book your San Diego to Santa Ana bus tickets online with Greyhound Mexico and Amtrak.
The distance between San Diego and Santa Ana is 132 km. The road distance is 146 km.
Greyhound Mexico operates a bus from San Diego to Santa Ana 3 times a day. Tickets cost $18–28 and the journey takes 1h 55m. Amtrak also services this route once daily.
