The bus between San Diego and St. Louis takes 46h 10m. There is at least one bus per day from San Diego to St. Louis. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run once daily between San Diego and St. Louis. The earliest departure is at 7:00 AM in the morning, and the last departure from San Diego is at 7:00 AM which arrives into St. Louis at 7:10 AM. All services require a transfer, and take on average 46h 10m. The schedules shown below are for the next available departures.
Want to know about travelling from San Diego to St. Louis? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from San Diego to St. Louis. However, there are services departing from San Diego station and arriving at St. Louis station via Los Angeles Union Station station. The journey, including transfers, takes approximately 46h 10m.
San Diego to St. Louis bus services, operated by Greyhound Mexico, depart from San Diego station.
San Diego to St. Louis bus services, operated by Greyhound Mexico, arrive at St Louis Bus Station.
Book your San Diego to St. Louis bus tickets online with Greyhound Mexico and Greyhound USA.
The distance between San Diego and St. Louis is 2,512.8 km. The road distance is 3,265 km.
You can take a bus from San Diego to St Louis Bus Station via Los Angeles Union Station in around 44h 10m.
