The average bus between San Donato di Lecce and Rome takes 10h 52m and the fastest bus takes 8h 57m. The bus service runs several times per day from San Donato di Lecce to Rome. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 4 hours between San Donato di Lecce and Rome. The earliest departure is at 7:26 AM in the morning, and the last departure from San Donato di Lecce is at 9:38 PM which arrives into Rome at 3:15 PM. All services require a transfer at Lecce and take an average of 10h 52m. The schedules shown below are for the next available departures.


10h 7m • 2 changes
Arrives next day


12h 42m • 2 changes
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9h 43m • 2 changes
Arrives next day


17h 37m • 2 changes


9h 54m • 2 changes


8h 57m • 2 changes


10h 7m • 2 changes
Arrives next day


9h 12m • 2 changes


9h 54m • 2 changes


8h 57m • 2 changes


10h 7m • 2 changes
Arrives next day


9h 12m • 2 changes


9h 54m • 2 changes


8h 57m • 2 changes


10h 7m • 2 changes
Arrives next day


9h 12m • 2 changes


9h 54m • 2 changes


8h 57m • 2 changes


10h 7m • 2 changes
Arrives next day


9h 12m • 2 changes


9h 54m • 2 changes


8h 57m • 2 changes


10h 7m • 2 changes
Arrives next day


9h 12m • 2 changes
Want to know about travelling from San Donato di Lecce to Rome? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from San Donato di Lecce to Rome. However, there are services departing from San Donato di Lecce station and arriving at Rome station via Roma, Autostazione Tiburtina. The journey, including transfers, takes approximately 10h 52m.
San Donato di Lecce to Rome bus services, operated by Ferrovie del Sud Est e Servizi Automobilistici S.r.l., depart from Lecce station.
San Donato di Lecce to Rome bus services, operated by Ferrovie del Sud Est e Servizi Automobilistici S.r.l., arrive at Roma, Autostazione Tiburtina station.
Book your San Donato di Lecce to Rome bus tickets online with Ferrovie del Sud Est e Servizi Automobilistici S.r.l., S.G.M. S.p.A. and FlixBus.
The distance between San Donato di Lecce and Rome is 509.6 km. The road distance is 626 km.
FlixBus operates a bus from Lecce to Roma, Autostazione Tiburtina every 4 hours. Tickets cost €50–90 and the journey takes 8h 15m.