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San Francisco to Chicago buses

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Trip Overview

The average bus between San Francisco and Chicago takes 2d 2h and the fastest bus takes 2d 1h. The bus runs, on average, 6 times per week from San Francisco to Chicago. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

2d 2h
Duration
2,298 mi
Distance
$500
Average price
6 times a week
Frequency

San Francisco to Chicago bus times

Buses run 6 times a week between San Francisco and Chicago. The service departs San Francisco at 12:45 PM in the afternoon, which arrives into Chicago at 16:25:00. All services require a transfer at Sparks Transit Center and take an average of 2d 2h. The schedules shown below are for the next available departures.

Departing Thursday, November 5, 2026

  •  → 

    Arrives +2 days

    Greyhound USAGreyhound USAGreyhound USA2d 1h • 2 changes

Departing Friday, November 6, 2026

  •  → 

    Arrives +2 days

    Greyhound USAGreyhound USAGreyhound USA2d 1h • 2 changes

Departing Saturday, November 7, 2026

  •  → 

    Arrives +2 days

    Greyhound USAGreyhound USAGreyhound USA2d 1h • 2 changes

Departing Sunday, November 8, 2026

  •  → 

    Arrives +2 days

    Greyhound USAGreyhound USAGreyhound USA2d 1h • 2 changes

Departing Monday, November 9, 2026

  •  → 

    Arrives +2 days

    Greyhound USAGreyhound USAGreyhound USA2d 1h • 2 changes

Frequently asked questions

Want to know about travelling from San Francisco to Chicago? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from San Francisco to Chicago.ExpandLaunch map view
  • Distance: 2,298.4 mi
  • Duration: 2d 2h

What companies run services between San Francisco, CA, USA and Chicago, IL, USA?

You can take a bus from San Francisco Bus Station to Chicago Bus Station via Sparks Transit Center and Denver Union Station in around 2d 2h.

Operators