Rome2Rio

San Francisco to Cincinnati buses

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Trip Overview

The average bus between San Francisco and Cincinnati takes 2d 23h and the fastest bus takes 2d 22h. The bus runs, on average, 5 times per week from San Francisco to Cincinnati. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

2d 23h
Duration
2,599 mi
Distance
$544
Average price
5 times a week
Frequency

San Francisco to Cincinnati bus times

Buses run 5 times a week between San Francisco and Cincinnati. The service departs San Francisco at 12:45 PM in the afternoon, which arrives into Cincinnati at 14:25:00. All services require a transfer at Sparks Transit Center and take an average of 2d 23h. The schedules shown below are for the next available departures.

Departing Wednesday, November 11, 2026

  •  → 

    Arrives +3 days

    Greyhound USAGreyhound USAGreyhound USAFlixbus USA2d 22h • 3 changes

Departing Thursday, November 12, 2026

  •  → 

    Arrives +3 days

    Greyhound USAGreyhound USAGreyhound USAFlixbus USA2d 22h • 3 changes

Departing Friday, November 13, 2026

  •  → 

    Arrives +3 days

    Greyhound USAGreyhound USAGreyhound USAFlixbus USA2d 22h • 3 changes

Departing Saturday, November 14, 2026

  •  → 

    Arrives +3 days

    Greyhound USAGreyhound USAGreyhound USAFlixbus USA2d 22h • 3 changes

Frequently asked questions

Want to know about travelling from San Francisco to Cincinnati? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from San Francisco to Cincinnati.ExpandLaunch map view
  • Distance: 2,599 mi
  • Duration: 2d 23h

What companies run services between San Francisco, CA, USA and Cincinnati, OH, USA?

You can take a bus from San Francisco Bus Station to Cincinnati via Sparks Transit Center, Denver Union Station, and Chicago Bus Station in around 2d 8h.

Operators