The average bus between San Francisco and Des Moines takes 40h 35m and the fastest bus takes 39h 35m. There is at least one bus per day from San Francisco to Des Moines. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run once daily between San Francisco and Des Moines. The earliest departure is at 1:30 PM in the afternoon, and the last departure from San Francisco is at 1:30 PM which arrives into Des Moines at 8:05 AM. All services require a transfer at Sparks Transit Center and take an average of 40h 35m. The schedules shown below are for the next available departures.
Want to know about travelling from San Francisco to Des Moines? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from San Francisco to Des Moines. However, there are services departing from San Francisco station and arriving at Des Moines station via Sparks Transit Center. The journey, including transfers, takes approximately 40h 35m.
San Francisco to Des Moines bus services, operated by Greyhound USA, depart from San Francisco Bus Station.
San Francisco to Des Moines bus services, operated by Greyhound USA, arrive at Des Moines station.
Book your San Francisco to Des Moines bus tickets online with Greyhound USA and Jefferson Lines.
The distance between San Francisco and Des Moines is 2,489.7 km. The road distance is 3,162 km.
You can take a bus from San Francisco Bus Station to Des Moines via Sparks Transit Center, Denver Union Station, and Denver in around 40h 54m.
