The average bus between San Francisco and Des Moines takes 42h 51m and the fastest bus takes 41h 45m. The bus runs, on average, 6 times per week from San Francisco to Des Moines. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 6 times a week between San Francisco and Des Moines. The earliest departure is at 1:10 PM in the afternoon, and the last departure from San Francisco is at 1:10 PM which arrives into Des Moines at 8:55 AM. All services require a transfer at Sparks Transit Center and take an average of 42h 51m. The schedules shown below are for the next available departures.
Want to know about travelling from San Francisco to Des Moines? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from San Francisco to Des Moines. However, there are services departing from San Francisco station and arriving at Des Moines station via Sparks Transit Center. The journey, including transfers, takes approximately 42h 51m.
San Francisco to Des Moines bus services, operated by Greyhound USA, depart from San Francisco Bus Station.
San Francisco to Des Moines bus services, operated by Greyhound USA, arrive at Des Moines station.
Book your San Francisco to Des Moines bus tickets online with Greyhound USA.
The distance between San Francisco and Des Moines is 2,489.7 km. The road distance is 3,163 km.
You can take a bus from San Francisco Bus Station to Des Moines via Sparks Transit Center and Denver Union Station in around 42h 10m.
