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San Francisco to Iowa City buses

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Trip Overview

The average bus between San Francisco and Iowa City takes 45h 21m and the fastest bus takes 44h 15m. The bus runs, on average, 6 times per week from San Francisco to Iowa City. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

45h 21m
Duration
2,075 mi
Distance
$450
Average price
6 times a week
Frequency

San Francisco to Iowa City bus times

Buses run 6 times a week between San Francisco and Iowa City. The service departs San Francisco at 1:10 PM in the afternoon, which arrives into Iowa City at 11:25:00. All services require a transfer at Sparks Transit Center and take an average of 45h 21m. The schedules shown below are for the next available departures.

Departing Tuesday, November 3, 2026

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    Arrives +2 days

    Greyhound USAGreyhound USAGreyhound USA44h 15m • 2 changes

Departing Wednesday, November 4, 2026

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    Arrives +2 days

    Greyhound USAGreyhound USAGreyhound USA44h 15m • 2 changes

Departing Thursday, November 5, 2026

  •  → 

    Arrives +2 days

    Greyhound USAGreyhound USAGreyhound USA44h 15m • 2 changes

Departing Friday, November 6, 2026

  •  → 

    Arrives +2 days

    Greyhound USAGreyhound USAGreyhound USA44h 15m • 2 changes

Departing Saturday, November 7, 2026

  •  → 

    Arrives +2 days

    Greyhound USAGreyhound USAGreyhound USA44h 15m • 2 changes

Frequently asked questions

Want to know about travelling from San Francisco to Iowa City? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from San Francisco to Iowa City.ExpandLaunch map view
  • Distance: 2,074.9 mi
  • Duration: 45h 21m

What companies run services between San Francisco, CA, USA and Iowa City, IA, USA?

You can take a bus from San Francisco Bus Station to Iowa City via Sparks Transit Center and Denver Union Station in around 44h 40m.

Operators