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San Francisco to Irvine buses

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Trip Overview

The average bus between San Francisco and Irvine takes 10h 27m and the fastest bus takes 10h 4m. The bus runs, on average, 3 times per week from San Francisco to Irvine. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

10h 27m
Duration
433 mi
Distance
$81
Average price
3 times a week
Frequency

San Francisco to Irvine bus times

Buses run 3 times a week between San Francisco and Irvine. The service departs San Francisco at 1:05 AM at night, which arrives into Irvine at 11:44:00. All services require a transfer at Anaheim Regional Transportation Intermodal Center and take an average of 10h 27m. The schedules shown below are for the next available departures.

Departing Thursday, November 5, 2026

  •  → 

    Flixbus USAOCTA10h 39m • 1 change

Departing Friday, November 6, 2026

  •  → 

    Flixbus USAOCTA10h 39m • 1 change

Departing Saturday, November 7, 2026

  •  → 

    Flixbus USAOCTA10h 4m • 1 change

Frequently asked questions

Want to know about travelling from San Francisco to Irvine? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from San Francisco to Irvine.ExpandLaunch map view
  • Distance: 432.8 mi
  • Duration: 10h 27m

What companies run services between San Francisco, CA, USA and Irvine, CA, USA?

Flixbus USA operates a bus from San Francisco to Anaheim Regional Transportation Intermodal Center once daily. Tickets cost $65–100 and the journey takes 9h 5m.

Operators