Rome2Rio

San Francisco to Mesa buses

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Trip Overview

The average bus between San Francisco and Mesa takes 31h 29m and the fastest bus takes 30h 31m. The bus runs, on average, 5 times per week from San Francisco to Mesa. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

31h 29m
Duration
875 mi
Distance
$167
Average price
5 times a week
Frequency

San Francisco to Mesa bus times

Buses run 5 times a week between San Francisco and Mesa. The service departs San Francisco at 1:05 AM at night, which arrives into Mesa at 08:36:00. All services require a transfer at Los Angeles Union Station and take an average of 31h 29m. The schedules shown below are for the next available departures.

Departing Thursday, November 12, 2026

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    Arrives next day

    Flixbus USAFlixbus USAFlixbus USAValley Metro30h 31m • 3 changes

Departing Friday, November 13, 2026

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    Arrives next day

    Flixbus USAFlixbus USAFlixbus USAValley Metro30h 45m • 3 changes

Departing Saturday, November 14, 2026

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    Arrives next day

    Flixbus USAFlixbus USAFlixbus USAValley Metro30h 40m • 3 changes

Departing Sunday, November 15, 2026

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    Arrives next day

    Flixbus USAFlixbus USAFlixbus USAValley Metro30h 31m • 3 changes

Departing Monday, November 16, 2026

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    Arrives next day

    Flixbus USAFlixbus USAFlixbus USAValley Metro35h 2m • 3 changes

Frequently asked questions

Want to know about travelling from San Francisco to Mesa? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from San Francisco to Mesa.ExpandLaunch map view
  • Distance: 875.3 mi
  • Duration: 31h 29m

What companies run services between San Francisco, CA, USA and Mesa, AZ, USA?

You can take a bus from San Francisco to University Dr & Mesa Dr via Los Angeles Union Station, Phoenix Sky Harbor Airport/44th Street Sky Train Station, Tempe, and University Dr & Rural Rd in around 21h 30m.

Operators