The average bus between San Francisco and Mesa takes 27h 14m and the fastest bus takes 26h 54m. There is at least one bus per day from San Francisco to Mesa. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run once daily between San Francisco and Mesa. The earliest departure is at 2:40 AM at night, and the last departure from San Francisco is at 2:40 AM which arrives into Mesa at 5:34 AM. All services require a transfer at Los Angeles Union Station and take an average of 27h 14m. The schedules shown below are for the next available departures.
Want to know about travelling from San Francisco to Mesa? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from San Francisco to Mesa. However, there are services departing from San Francisco station and arriving at Mesa station via Los Angeles Union Station station. The journey, including transfers, takes approximately 27h 14m.
San Francisco to Mesa bus services, operated by Greyhound-us, depart from San Francisco station.
San Francisco to Mesa bus services, operated by Greyhound-us, arrive at Phoenix Sky Harbor Airport/44th Street Sky Train Station.
Book your San Francisco to Mesa bus tickets online with Greyhound-us, CBX Cross Border Express and Valley Metro.
The distance between San Francisco and Mesa is 1,072.5 km. The road distance is 1,326 km.
You can take a bus from San Francisco to Mesa Dr/Main St via Los Angeles Union Station, Phoenix Sky Harbor Airport/44th Street Sky Train Station, and 44th St/Washington in around 17h 45m.