The bus between San Francisco and San Luis Obispo takes 4h 30m. The bus runs, on average, 5 times per week from San Francisco to San Luis Obispo. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 5 times a week between San Francisco and San Luis Obispo. The earliest departure is at 7:10 AM in the morning, and the last departure from San Francisco is at 7:10 AM which arrives into San Luis Obispo at 11:40 AM. All services run direct with no transfers required, and take on average 4h 30m. The schedules shown below are for the next available departures.
Want to know about travelling from San Francisco to San Luis Obispo? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
Yes, there is a direct bus departing from San Francisco station and arriving at San Luis Obispo station. Services depart 5 times a week, and operate 4 times a week. The journey takes approximately 4h 30m.
San Francisco to San Luis Obispo bus services, operated by Flixbus USA, depart from San Francisco station.
San Francisco to San Luis Obispo bus services, operated by Flixbus USA, arrive at San Luis Obispo Railroad Museum station.
Book your San Francisco to San Luis Obispo bus tickets online with Flixbus USA.
The distance between San Francisco and San Luis Obispo is 318.6 km. The road distance is 376 km.
Flixbus USA operates a bus from San Francisco to San Luis Obispo Railroad Museum once daily. Tickets cost $35–65 and the journey takes 4h 30m.