The average bus between San Francisco and Santa Ana takes 11h 50m and the fastest bus takes 9h 12m. There is at least one bus per day from San Francisco to Santa Ana. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run once daily between San Francisco and Santa Ana. The earliest departure is at 1:00 AM at night, and the last departure from San Francisco is at 1:00 AM which arrives into Santa Ana at 10:16 AM. All services require a transfer at Anaheim Regional Transportation Intermodal Center and take an average of 11h 50m. The schedules shown below are for the next available departures.
Want to know about travelling from San Francisco to Santa Ana? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from San Francisco to Santa Ana. However, there are services departing from San Francisco station and arriving at Santa Ana station via Anaheim Regional Transportation Intermodal Center. The journey, including transfers, takes approximately 11h 50m.
San Francisco to Santa Ana bus services, operated by Flixbus USA, depart from San Francisco station.
San Francisco to Santa Ana bus services, operated by Flixbus USA, arrive at Anaheim Regional Transportation Intermodal Center station.
Book your San Francisco to Santa Ana bus tickets online with Flixbus USA and OCTA.
The distance between San Francisco and Santa Ana is 607.6 km. The road distance is 686 km.
Flixbus USA operates a bus from San Francisco to Anaheim Regional Transportation Intermodal Center once daily. Tickets cost $60–95 and the journey takes 8h 40m.
