- Distance: 428 mi
- Duration: 11h 30m
The bus between San Francisco and Santa Ana takes 11h 30m. There is at least one bus per day from San Francisco to Santa Ana. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run once daily between San Francisco and Santa Ana. The earliest departure is at 10:30 PM at night, and the last departure from San Francisco is at 10:30 PM which arrives into Santa Ana at 10:00 AM. All services run direct with no transfers required, and take on average 11h 30m. The schedules shown below are for the next available departures.
Want to know about travelling from San Francisco to Santa Ana? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
Yes, there is a direct bus departing from San Francisco station and arriving at Santa Ana station. Services depart once daily, and operate Twice daily. The journey takes approximately 11h 30m.
San Francisco to Santa Ana bus services, operated by Greyhound USA, depart from San Francisco Bus Station.
San Francisco to Santa Ana bus services, operated by Greyhound USA, arrive at Santa Ana Bus Stop station.
Book your San Francisco to Santa Ana bus tickets online with Greyhound USA.
The distance between San Francisco and Santa Ana is 607.6 km. The road distance is 689 km.
Jefferson Lines operates a bus from San Francisco Bus Station to Santa Ana Bus Stop once daily. Tickets cost $100–140 and the journey takes 11h 20m. Greyhound USA also services this route once daily.
