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The bus between San Francisco and St. Louis takes 2d 4h. There is at least one bus per day from San Francisco to St. Louis. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run once daily between San Francisco and St. Louis. The service departs San Francisco at 1:05 AM at night, which arrives into St. Louis at 07:05:00. All services require a transfer, and take on average 2d 4h. The schedules shown below are for the next available departures.
Want to know about travelling from San Francisco to St. Louis? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from San Francisco to St. Louis. However, there are services departing from San Francisco station and arriving at St Louis Bus Station via Los Angeles Union Station. The journey, including transfers, takes approximately 2 days 4h.
San Francisco to St. Louis bus services, operated by Flixbus USA, depart from San Francisco station.
San Francisco to St. Louis bus services, operated by Greyhound USA, arrive at St Louis Bus Station.
Book your San Francisco to St. Louis bus tickets online with Omio and FlixBus.
The distance between San Francisco and St. Louis is 2802.7 km. The road distance is 3297 km.
You can take a bus from San Francisco to St Louis Bus Station via Los Angeles Union Station in around 2d 1h.
