The bus between San Luis Obispo and San Diego takes 17h 35m. The bus runs, on average, 4 times per week from San Luis Obispo to San Diego. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 4 times a week between San Luis Obispo and San Diego. The earliest departure is at 12:00 PM in the afternoon, and the last departure from San Luis Obispo is at 12:00 PM which arrives into San Diego at 5:35 AM. All services require a transfer at Los Angeles Union Station and take an average of 17h 35m. The schedules shown below are for the next available departures.
Want to know about travelling from San Luis Obispo to San Diego? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from San Luis Obispo to San Diego. However, there are services departing from San Luis Obispo station and arriving at San Diego station via Los Angeles Union Station station. The journey, including transfers, takes approximately 17h 35m.
San Luis Obispo to San Diego bus services, operated by Flixbus USA, depart from San Luis Obispo Railroad Museum station.
San Luis Obispo to San Diego bus services, operated by Flixbus USA, arrive at San Diego station.
Book your San Luis Obispo to San Diego bus tickets online with Flixbus USA and Amtrak.
The distance between San Luis Obispo and San Diego is 430.6 km. The road distance is 506 km.
You can take a bus from San Luis Obispo Railroad Museum to San Diego via Los Angeles Union Station and Los Angeles in around 8h 20m.
