The bus between San Luis Obispo and San Francisco takes 4h 35m. The bus runs, on average, 4 times per week from San Luis Obispo to San Francisco. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 4 times a week between San Luis Obispo and San Francisco. The earliest departure is at 1:20 PM in the afternoon, and the last departure from San Luis Obispo is at 1:20 PM which arrives into San Francisco at 5:55 PM. All services run direct with no transfers required, and take on average 4h 35m. The schedules shown below are for the next available departures.
Want to know about travelling from San Luis Obispo to San Francisco? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
Yes, there is a direct bus departing from San Luis Obispo station and arriving at San Francisco station. Services depart 4 times a week, and operate 4 times a week. The journey takes approximately 4h 35m.
San Luis Obispo to San Francisco bus services, operated by Flixbus USA, depart from San Luis Obispo Railroad Museum station.
San Luis Obispo to San Francisco bus services, operated by Flixbus USA, arrive at San Francisco station.
Book your San Luis Obispo to San Francisco bus tickets online with Flixbus USA.
The distance between San Luis Obispo and San Francisco is 318.6 km. The road distance is 376 km.
Flixbus USA operates a bus from San Luis Obispo Railroad Museum to San Francisco 4 times a week. Tickets cost $35–60 and the journey takes 4h 35m.