The average bus between San Mateo and Santa Rosa takes 2h 57m and the fastest bus takes 2h 43m. There is a bus service every few hours from San Mateo to Santa Rosa. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run hourly between San Mateo and Santa Rosa. The earliest departure is at 4:14 AM at night, and the last departure from San Mateo is at 11:39 PM which arrives into Santa Rosa at 2:30 AM. All services require a transfer at SFO Airport Terminal 2-Lower Level and take an average of 2h 57m. The schedules shown below are for the next available departures.
Arrives next day

2h 49m • 1 change
Arrives next day

2h 51m • 1 change

2h 52m • 1 change

2h 52m • 1 change

2h 51m • 1 change

2h 50m • 1 change

3h 16m • 1 change

3h 16m • 1 change

2h 46m • 1 change

2h 44m • 1 change

3h 16m • 1 change

3h 16m • 1 change

3h 16m • 1 change

2h 45m • 1 change
Want to know about travelling from San Mateo to Santa Rosa? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from San Mateo to Santa Rosa. However, there are services departing from San Mateo station and arriving at Santa Rosa station via SFO Airport Terminal 2-Lower Level. The journey, including transfers, takes approximately 2h 57m.
San Mateo to Santa Rosa bus services, operated by SamTrans, depart from S Delaware St & 2nd Ave station.
San Mateo to Santa Rosa bus services, operated by SamTrans, arrive at Santa Rosa station.
The distance between San Mateo and Santa Rosa is 103.4 km. The road distance is 126 km.
You can take a bus from S Delaware St & 2nd Ave to Santa Rosa via SFO Airport Terminal 2-Lower Level and San Francisco Airport in around 3h 28m.