The average bus between San Mateo and Santana Row takes 2h 50m and the fastest bus takes 2h 11m. The bus runs at least 2 times per hour from San Mateo to Santana Row. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 30 minutes between San Mateo and Santana Row. The earliest departure is at 3:02 AM at night, and the last departure from San Mateo is at 6:51 PM which arrives into Santana Row at 9:52 PM. All services require a transfer at Palo Alto Transit Center and take an average of 2h 50m. The schedules shown below are for the next available departures.


2h 45m • 2 changes


2h 32m • 2 changes


2h 32m • 2 changes


2h 22m • 2 changes
Want to know about travelling from San Mateo to Santana Row? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from San Mateo to Santana Row. However, there are services departing from San Mateo station and arriving at Santana Row station via Palo Alto Transit Ctr-Bay 1. The journey, including transfers, takes approximately 2h 50m.
San Mateo to Santana Row bus services, operated by SamTrans, depart from El Camino Real & 4th Ave station.
San Mateo to Santana Row bus services, operated by SamTrans, arrive at Santa Clara Transit Center station.
The distance between San Mateo and Santana Row is 42.9 km. The road distance is 51 km.
You can take a bus from El Camino Real & 4th Ave to Winchester & Olsen via Palo Alto Transit Center and Santa Clara Transit Center in around 2h 43m.