The average bus between San Salvo and Perugia takes 6h 55m and the fastest bus takes 6h 10m. The bus service runs several times per day from San Salvo to Perugia. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 4 hours between San Salvo and Perugia. The earliest departure is at 2:00 AM at night, and the last departure from San Salvo is at 4:50 PM which arrives into Perugia at 11:10 PM. All services require a transfer, and take on average 6h 55m. The schedules shown below are for the next available departures.

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Want to know about travelling from San Salvo to Perugia? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from San Salvo to Perugia. However, there are services departing from San Salvo station and arriving at Perugia station via Roma, Autostazione Tiburtina. The journey, including transfers, takes approximately 6h 55m.
San Salvo to Perugia bus services, operated by Dicarlo Bus, depart from San Salvo station.
San Salvo to Perugia bus services, operated by Dicarlo Bus, arrive at Perugia station.
Book your San Salvo to Perugia bus tickets online with Dicarlo Bus, FlixBus and Sulga Autolinee.
The distance between San Salvo and Perugia is 225.7 km. The road distance is 456 km.
You can take a bus from San Salvo to Perugia via Roma, Autostazione Tiburtina in around 7h 10m.