Rome2Rio

San Sano to Rome buses

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Trip Overview

The average bus between San Sano and Rome takes 6h 11m and the fastest bus takes 3h 21m. The bus service runs several times per day from San Sano to Rome. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

6h 11m
Duration
251 km
Distance
€22
Average price
Twice daily
Frequency

San Sano to Rome bus times

Buses run twice daily between San Sano and Rome. The earliest departure is at 8:03 AM in the morning, and the last departure from San Sano is at 3:34 PM which arrives into Rome at 10:35 PM. All services require a transfer, and take on average 6h 11m. The schedules shown below are for the next available departures.

Departing Saturday, November 7, 2026

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    Autolinee ToscaneFlixBus3h 21m • 1 change
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    Autolinee ToscaneFlixBus7h • 1 change

Departing Monday, November 9, 2026

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    Autolinee ToscaneFlixBus3h 21m • 1 change
  •  → 

    Autolinee ToscaneFlixBus7h 10m • 1 change

Departing Tuesday, November 10, 2026

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    Autolinee ToscaneFlixBus3h 21m • 1 change
  •  → 

    Autolinee ToscaneFlixBus8h 20m • 1 change

Departing Wednesday, November 11, 2026

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    Autolinee ToscaneFlixBus3h 21m • 1 change
  •  → 

    Arrives next day

    Autolinee ToscaneFlixBus17h 15m • 1 change

Departing Thursday, November 12, 2026

  •  → 

    Autolinee ToscaneFlixBus3h 21m • 1 change
  •  → 

    Autolinee ToscaneFlixBus7h 10m • 1 change

Departing Friday, November 13, 2026

  •  → 

    Autolinee ToscaneFlixBus3h 21m • 1 change
  •  → 

    Autolinee ToscaneFlixBus7h 10m • 1 change

Frequently asked questions

Want to know about travelling from San Sano to Rome? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from San Sano to Rome.ExpandLaunch map view
  • Distance: 251 km
  • Duration: 6h 11m

What companies run services between San Sano, Italy and Rome, Italy?

FlixBus operates a bus from Siena to Roma, Autostazione Tiburtina hourly. Tickets cost €20–30 and the journey takes 2h 50m. AutoLinee Moretti also services this route 3 times a week.

Operators