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San Sano to Rome buses

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Trip Overview

The bus between San Sano and Rome takes 3h 50m. The bus runs, on average, 2 times per week from San Sano to Rome. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

3h 50m
Duration
251 km
Distance
€23
Average price
Twice a week
Frequency

San Sano to Rome bus times

Buses run twice a week between San Sano and Rome. The earliest departure is at 3:24 PM in the afternoon, and the last departure from San Sano is at 3:24 PM which arrives into Rome at 7:15 PM. All services require a transfer, and take on average 3h 50m. The schedules shown below are for the next available departures.

Departing Monday, October 19, 2026

  •  → 

    Autolinee ToscaneItabus S.p.A.3h 50m • 1 change

Departing Tuesday, October 20, 2026

  •  → 

    Autolinee ToscaneItabus S.p.A.3h 50m • 1 change

Frequently asked questions

Want to know about travelling from San Sano to Rome? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from San Sano to Rome.ExpandLaunch map view
  • Distance: 251.1 km
  • Duration: 3h 50m

What companies run services between San Sano, Italy and Rome, Italy?

Itabus S.p.A. operates a bus from Siena Central Train Station to Rome Tiburtina Largo Mazzoni once daily. Tickets cost €12–22 and the journey takes 2h 50m. FlixBus also services this route twice daily.

Operators