Rome2Rio

San Sano to Rome buses

Find Transport to Rome

View schedule

Trip Overview

The average bus between San Sano and Rome takes 3h 48m and the fastest bus takes 3h 40m. The bus runs, on average, 6 times per week from San Sano to Rome. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

3h 48m
Duration
251 km
Distance
€23
Average price
6 times a week
Frequency

San Sano to Rome bus times

Buses run 6 times a week between San Sano and Rome. The earliest departure is at 3:24 PM in the afternoon, and the last departure from San Sano is at 3:34 PM which arrives into Rome at 7:15 PM. All services require a transfer, and take on average 3h 48m. The schedules shown below are for the next available departures.

Departing Saturday, October 10, 2026

  •  → 

    Autolinee ToscaneItabus S.p.A.3h 40m • 1 change

Departing Monday, October 12, 2026

  •  → 

    Autolinee ToscaneItabus S.p.A.3h 50m • 1 change

Departing Tuesday, October 13, 2026

  •  → 

    Autolinee ToscaneItabus S.p.A.3h 50m • 1 change

Departing Wednesday, October 14, 2026

  •  → 

    Autolinee ToscaneItabus S.p.A.3h 50m • 1 change

Departing Thursday, October 15, 2026

  •  → 

    Autolinee ToscaneItabus S.p.A.3h 50m • 1 change

Departing Friday, October 16, 2026

  •  → 

    Autolinee ToscaneItabus S.p.A.3h 50m • 1 change

Frequently asked questions

Want to know about travelling from San Sano to Rome? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from San Sano to Rome.ExpandLaunch map view
  • Distance: 251.1 km
  • Duration: 3h 48m

What companies run services between San Sano, Italy and Rome, Italy?

Itabus S.p.A. operates a bus from Siena Central Train Station to Rome Tiburtina Largo Mazzoni once daily. Tickets cost €12–21 and the journey takes 2h 50m. FlixBus also services this route twice daily.

Operators