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San Ysidro to Irvine buses

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Trip Overview

The average bus between San Ysidro and Irvine takes 4h 47m and the fastest bus takes 3h 2m. The bus service runs several times per day from San Ysidro to Irvine. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

4h 47m
Duration
114 mi
Distance
$29
Average price
Every 4 hours
Frequency

San Ysidro to Irvine bus times

Buses run every 4 hours between San Ysidro and Irvine. The earliest departure is at 1:02 AM at night, and the last departure from San Ysidro is at 11:02 PM which arrives into Irvine at 8:53 AM. All services require a transfer at San Ysidro Transit Center and take an average of 4h 47m. The schedules shown below are for the next available departures.

Departing Thursday, November 12, 2026

  •  → 

    San Diego Metro TransitLimousine ExpressOCTA4h 19m • 2 changes
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    San Diego Metro TransitLimousine ExpressOCTA3h 2m • 2 changes
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    San Diego Metro TransitGreyhound USAOCTA3h 15m • 2 changes
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    San Diego Metro TransitLimousine ExpressOCTA3h 31m • 2 changes

Departing Friday, November 13, 2026

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    San Diego Metro TransitGreyhound USAOCTA7h 51m • 2 changes
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    San Diego Metro TransitLimousine ExpressOCTA4h 45m • 2 changes
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    San Diego Metro TransitLimousine ExpressOCTA4h 17m • 2 changes
  •  → 

    San Diego Metro TransitLimousine ExpressOCTA4h 19m • 2 changes
  • Show more

Departing Saturday, November 14, 2026

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    San Diego Metro TransitGreyhound USAOCTA7h 35m • 2 changes
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    San Diego Metro TransitLimousine ExpressOCTA4h 31m • 2 changes
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    San Diego Metro TransitLimousine ExpressOCTA4h 19m • 2 changes
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    San Diego Metro TransitLimousine ExpressOCTA3h 11m • 2 changes
  • Show more

Departing Sunday, November 15, 2026

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    Arrives next day

    San Diego Metro TransitLimousine ExpressOCTA10h 8m • 2 changes
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    Arrives next day

    San Diego Metro TransitGreyhound USAOCTA9h 51m • 2 changes

Departing Monday, November 16, 2026

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    San Diego Metro TransitLimousine ExpressOCTA4h 45m • 2 changes
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    San Diego Metro TransitLimousine ExpressOCTA4h 17m • 2 changes
  •  → 

    San Diego Metro TransitLimousine ExpressOCTA4h 19m • 2 changes
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    San Diego Metro TransitLimousine ExpressOCTA3h 2m • 2 changes
  • Show more

Departing Tuesday, November 17, 2026

  •  → 

    San Diego Metro TransitGreyhound USAOCTA7h 51m • 2 changes
  •  → 

    San Diego Metro TransitLimousine ExpressOCTA4h 45m • 2 changes
  •  → 

    San Diego Metro TransitLimousine ExpressOCTA4h 17m • 2 changes
  •  → 

    San Diego Metro TransitLimousine ExpressOCTA4h 19m • 2 changes
  • Show more

Departing Wednesday, November 18, 2026

  •  → 

    San Diego Metro TransitGreyhound USAOCTA7h 51m • 2 changes
  •  → 

    San Diego Metro TransitLimousine ExpressOCTA4h 45m • 2 changes
  •  → 

    San Diego Metro TransitLimousine ExpressOCTA4h 17m • 2 changes
  •  → 

    San Diego Metro TransitLimousine ExpressOCTA4h 19m • 2 changes
  • Show more

Frequently asked questions

Want to know about travelling from San Ysidro to Irvine? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from San Ysidro to Irvine.ExpandLaunch map view
  • Distance: 114.3 mi
  • Duration: 4h 47m

What companies run services between San Ysidro, CA, USA and Irvine, CA, USA?

You can take a bus from San Ysidro Bl & I-805 to Campus-University Center via San Ysidro Transit Center, San Ysidro, Santa Ana, and The Depot At Santa Ana Dock 3 in around 3h 50m.

Operators