Sansepolcro to Siena Buses

Sansepolcro to Siena buses

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Trip Overview

The average bus between Sansepolcro and Siena takes 2h 48m and the fastest bus takes 2h 14m. The bus service runs several times per day from Sansepolcro to Siena. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

2h 48m
Duration: 115 km
Distance: €9
Average price: Every 4 hours
Frequency

Bus

best

Take the bus from Sansepolcro Via Marconi to Arezzo Terminalbus Si381 / ...
Take the bus from Arezzo Terminal to Porta Pispinibus 138

3h 11m

€7–10

Sansepolcro to Siena bus times

Buses run every 4 hours between Sansepolcro and Siena. The earliest departure is at 5:19 AM in the morning, and the last departure from Sansepolcro is at 7:26 PM which arrives into Siena at 9:40 PM. All services require a transfer, and take on average 2h 48m. The schedules shown below are for the next available departures.

Departing Thursday, September 17, 2026

7:26 PM → 9:40 PM
2h 14m • 1 change

Departing Friday, September 18, 2026

5:19 AM → 7:45 AM
2h 26m • 1 change
6:04 AM → 8:40 AM
2h 36m • 1 change
6:54 AM → 9:45 AM
2h 51m • 1 change
11:09 AM → 2:50 PM
3h 41m • 1 change
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Departing Saturday, September 19, 2026

5:19 AM → 7:45 AM
2h 26m • 1 change
6:05 AM → 8:40 AM
2h 35m • 1 change
6:55 AM → 9:50 AM
2h 55m • 1 change
11:09 AM → 2:50 PM
3h 41m • 1 change
Show more

Departing Sunday, September 20, 2026

7:00 PM → 9:50 PM
2h 50m • 1 change

Departing Monday, September 21, 2026

5:19 AM → 7:45 AM
2h 26m • 1 change
6:04 AM → 8:40 AM
2h 36m • 1 change
7:10 AM → 9:45 AM
2h 35m • 1 change
11:09 AM → 2:50 PM
3h 41m • 1 change
Show more

Departing Tuesday, September 22, 2026

5:19 AM → 7:45 AM
2h 26m • 1 change
6:04 AM → 8:40 AM
2h 36m • 1 change
6:54 AM → 9:45 AM
2h 51m • 1 change
11:09 AM → 2:50 PM
3h 41m • 1 change
Show more

Departing Wednesday, September 23, 2026

5:19 AM → 7:45 AM
2h 26m • 1 change
6:04 AM → 8:40 AM
2h 36m • 1 change
6:54 AM → 9:45 AM
2h 51m • 1 change
11:09 AM → 2:50 PM
3h 41m • 1 change
Show more

Frequently asked questions

Want to know about travelling from Sansepolcro to Siena? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Trip Overview

Bus