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Santa Ana to Louisville buses

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Trip Overview

The average bus between Santa Ana and Louisville takes 3d 2h and the fastest bus takes 3d 1h. The bus runs, on average, 4 times per week from Santa Ana to Louisville. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

3d 2h
Duration
2,219 mi
Distance
$565
Average price
4 times a week
Frequency

Santa Ana to Louisville bus times

Buses run 4 times a week between Santa Ana and Louisville. The service departs Santa Ana at 9:10 AM in the morning, which arrives into Louisville at 13:45:00. All services require a transfer at Los Angeles Union Station and take an average of 3d 2h. The schedules shown below are for the next available departures.

Departing Friday, October 30, 2026

  •  → 

    Arrives +3 days

    Greyhound MexicoGreyhound USAGreyhound USAMiller Transportation3d 2h • 3 changes

Departing Saturday, October 31, 2026

  •  → 

    Arrives +3 days

    Greyhound MexicoGreyhound USAGreyhound USAMiller Transportation3d 2h • 3 changes

Departing Sunday, November 1, 2026

  •  → 

    Arrives +3 days

    Greyhound MexicoGreyhound USAGreyhound USAMiller Transportation3d 1h • 3 changes

Departing Monday, November 2, 2026

  •  → 

    Arrives +3 days

    Greyhound MexicoGreyhound USAGreyhound USAMiller Transportation3d 1h • 3 changes

Frequently asked questions

Want to know about travelling from Santa Ana to Louisville? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Santa Ana to Louisville.ExpandLaunch map view
  • Distance: 2,218.7 mi
  • Duration: 3d 2h

What companies run services between Santa Ana, CA, USA and Louisville, KY, USA?

You can take a bus from Santa Ana to Louisville, KY via Los Angeles Union Station, St Louis Bus Station, and Evansville, IN in around 2d 1h.

Operators