The average bus between Santa Ana and Mission Beach takes 2h 43m and the fastest bus takes 2h 7m. The bus service runs several times per day from Santa Ana to Mission Beach. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Santa Ana and Mission Beach. The earliest departure is at 10:00 AM in the morning, and the last departure from Santa Ana is at 10:05 PM which arrives into Mission Beach at 12:12 AM. All services require a transfer at San Diego and take an average of 2h 43m. The schedules shown below are for the next available departures.

2h 17m • 1 change

2h 15m • 1 change
Arrives next day

2h 7m • 1 change

2h 17m • 1 change

2h 15m • 1 change
Arrives next day

2h 7m • 1 change

2h 17m • 1 change

2h 15m • 1 change
Arrives next day

2h 7m • 1 change

2h 22m • 1 change

2h 24m • 1 change
Arrives next day

2h 7m • 1 change

2h 22m • 1 change

2h 24m • 1 change
Arrives next day

7h 24m • 1 change
Want to know about travelling from Santa Ana to Mission Beach? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Santa Ana to Mission Beach. However, there are services departing from Santa Ana station and arriving at Mission Beach station via San Diego. The journey, including transfers, takes approximately 2h 43m.
Santa Ana to Mission Beach bus services, operated by Greyhound USA, depart from Santa Ana Bus Stop station.
Santa Ana to Mission Beach bus services, operated by Greyhound USA, arrive at San Diego station.
The distance between Santa Ana and Mission Beach is 121.4 km. The road distance is 139 km.
Flixbus USA operates a bus from Santa Ana Bus Stop to San Diego twice daily. Tickets cost $12–20 and the journey takes 1h 15m.