Santa Ana to Nogales Buses

Trip Overview

The average bus between Santa Ana and Nogales takes 14h 37m and the fastest bus takes 12h 30m. The bus service runs several times per day from Santa Ana to Nogales. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

14h 37m
Duration: 978 km
Distance: $2,515
Average price: Every 4 hours
Frequency

Bus

best

Take the bus from Santa Ana to Huntington Parkbus Lxus 3126 / ...
Take the bus from Huntington Park to Nogales, AZbus Huntington Park / ...

11h 32m

$2,169–3,063

Santa Ana to Nogales bus times

Buses run every 4 hours between Santa Ana and Nogales. The earliest departure is at 1:00 AM at night, and the last departure from Santa Ana is at 10:00 PM which arrives into Nogales at 7:30 AM. All services require a transfer, and take on average 14h 37m. The schedules shown below are for the next available departures.

Departing Sunday, October 18, 2026

12:00 PM → 9:30 PM
12h 30m • 1 change
1:40 PM → 4:10 AM
Arrives next day
14h 30m • 1 change
3:45 PM → 2:00 AM
Arrives next day
13h 15m • 1 change
3:45 PM → 4:20 AM
Arrives next day
12h 35m • 1 change
Show more

Departing Monday, October 19, 2026

1:00 AM → 9:00 PM
23h • 1 change
12:00 PM → 9:30 PM
12h 30m • 1 change
1:40 PM → 4:10 AM
Arrives next day
14h 30m • 1 change
3:45 PM → 2:00 AM
Arrives next day
13h 15m • 1 change
Show more

Departing Tuesday, October 20, 2026

1:00 AM → 9:00 PM
23h • 1 change
12:00 PM → 9:30 PM
12h 30m • 1 change
1:40 PM → 4:10 AM
Arrives next day
14h 30m • 1 change
3:45 PM → 2:00 AM
Arrives next day
13h 15m • 1 change
Show more

Departing Wednesday, October 21, 2026

1:00 AM → 9:00 PM
23h • 1 change
12:00 PM → 9:30 PM
12h 30m • 1 change
1:40 PM → 4:10 AM
Arrives next day
14h 30m • 1 change
3:45 PM → 2:00 AM
Arrives next day
13h 15m • 1 change
Show more

Departing Thursday, October 22, 2026

1:00 AM → 9:00 PM
23h • 1 change
12:00 PM → 9:30 PM
12h 30m • 1 change
1:40 PM → 4:10 AM
Arrives next day
14h 30m • 1 change
3:45 PM → 2:00 AM
Arrives next day
13h 15m • 1 change
Show more

Departing Friday, October 23, 2026

1:00 AM → 9:00 PM
23h • 1 change
12:00 PM → 9:30 PM
12h 30m • 1 change
1:40 PM → 4:10 AM
Arrives next day
14h 30m • 1 change
3:45 PM → 2:00 AM
Arrives next day
13h 15m • 1 change
Show more

Departing Saturday, October 24, 2026

1:00 AM → 9:00 PM
23h • 1 change
12:00 PM → 9:30 PM
12h 30m • 1 change
1:40 PM → 4:10 AM
Arrives next day
14h 30m • 1 change
3:45 PM → 2:00 AM
Arrives next day
13h 15m • 1 change
Show more

Frequently asked questions

Want to know about travelling from Santa Ana to Nogales? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.