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The average bus between Santa Ana and Otay Mesa takes 4h 14m and the fastest bus takes 3h 9m. The bus service runs several times per day from Santa Ana to Otay Mesa. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 4 hours between Santa Ana and Otay Mesa. The earliest departure is at 5:55 AM in the morning, and the last departure from Santa Ana is at 10:05 PM which arrives into Otay Mesa at 5:03 AM. All services require a transfer at San Ysidro and take an average of 4h 14m. The schedules shown below are for the next available departures.
4h 9m • 2 changes
3h 19m • 2 changes
3h 44m • 2 changes3h 30m • 2 changes3h 59m • 2 changes4h 9m • 2 changes3h 19m • 2 changes3h 44m • 2 changes3h 59m • 2 changes4h 9m • 2 changes3h 19m • 2 changes3h 44m • 2 changes4h 59m • 2 changes4h 44m • 2 changes3h 54m • 2 changes3h 19m • 2 changes4h 14m • 2 changes3h 59m • 2 changes3h 9m • 2 changes3h 34m • 2 changes3h 59m • 2 changes4h 9m • 2 changes3h 19m • 2 changes3h 44m • 2 changes3h 59m • 2 changes4h 9m • 2 changes3h 19m • 2 changes3h 44m • 2 changesWant to know about travelling from Santa Ana to Otay Mesa? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Santa Ana to Otay Mesa. However, there are services departing from Santa Ana station and arriving at San Ysidro station via San Ysidro station. The journey, including transfers, takes approximately 4h 14m.
Santa Ana to Otay Mesa bus services, operated by Limousine Express, depart from Santa Ana station.
Santa Ana to Otay Mesa bus services, operated by Limousine Express, arrive at San Ysidro station.
The distance between Santa Ana and Otay Mesa is 154.9 km. The road distance is 169 km.
Limousine Express operates a bus from Santa Ana to San Ysidro 5 times a day. Tickets cost $30–45 and the journey takes 1h 50m. Two other operators also service this route.
