The average bus between Santa Ana and San Clemente takes 1h 55m and the fastest bus takes 1h 41m. There is an hourly bus service from Santa Ana to San Clemente. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run hourly between Santa Ana and San Clemente. The earliest departure is at 4:51 AM at night, and the last departure from Santa Ana is at 8:22 PM which arrives into San Clemente at 10:04 PM. All services require a transfer, and take on average 1h 55m. The schedules shown below are for the next available departures.

1h 57m • 1 change

1h 50m • 1 change

1h 52m • 1 change

1h 49m • 1 change

1h 43m • 1 change

1h 43m • 1 change

2h 3m • 1 change

2h 3m • 1 change

1h 43m • 1 change

1h 43m • 1 change

2h 3m • 1 change

2h 3m • 1 change
Want to know about travelling from Santa Ana to San Clemente? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Santa Ana to San Clemente. However, there are services departing from Santa Ana station and arriving at San Clemente station via Laguna Hills Trans Ctr Dock 6. The journey, including transfers, takes approximately 1h 55m.
Santa Ana to San Clemente bus services, operated by OCTA, depart from Civic Center-Main station.
Santa Ana to San Clemente bus services, operated by OCTA, arrive at Calle De Los Molinos-Avd Pico station.
Book your Santa Ana to San Clemente bus tickets online with OCTA.
The distance between Santa Ana and San Clemente is 42.6 km. The road distance is 61 km.
You can take a bus from Civic Center-Main to Calle De Los Molinos-Avd Pico via Laguna Hills Trans Ctr Dock 7 in around 2h 9m.