The average bus between Santa Ana and San Diego takes 1h 48m and the fastest bus takes 1h 45m. The bus service runs several times per day from Santa Ana to San Diego. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 4 times a day between Santa Ana and San Diego. The earliest departure is at 7:35 AM in the morning, and the last departure from Santa Ana is at 10:00 PM which arrives into San Diego at 11:50 PM. All services run direct with no transfers required, and take on average 1h 48m. The schedules shown below are for the next available departures.
Want to know about travelling from Santa Ana to San Diego? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
Yes, there is a direct bus departing from Santa Ana station and arriving at San Diego station. Services depart 4 times a day, and operate 3 times a day. The journey takes approximately 1h 48m.
Santa Ana to San Diego bus services, operated by Greyhound Mexico, depart from Santa Ana station.
Santa Ana to San Diego bus services, operated by Greyhound Mexico, arrive at San Diego station.
Book your Santa Ana to San Diego bus tickets online with Greyhound Mexico and Flixbus USA.
The distance between Santa Ana and San Diego is 132 km. The road distance is 145 km.
Greyhound Mexico operates a bus from Santa Ana to San Diego 3 times a day. Tickets cost $18–28 and the journey takes 1h 55m. Two other operators also service this route.