The average bus between Santa Ana and San Francisco takes 13h 59m and the fastest bus takes 9h 22m. The bus runs, on average, 5 times per week from Santa Ana to San Francisco. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 5 times a week between Santa Ana and San Francisco. The earliest departure is at 12:07 AM at night, and the last departure from Santa Ana is at 11:07 PM which arrives into San Francisco at 8:30 AM. All services require a transfer at Artic - Dock 4 and take an average of 13h 59m. The schedules shown below are for the next available departures.
Want to know about travelling from Santa Ana to San Francisco? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Santa Ana to San Francisco. However, there are services departing from Anaheim Regional Transportation Intermodal Center station and arriving at San Francisco station via San Francisco station. The journey, including transfers, takes approximately 13h 59m.
Santa Ana to San Francisco bus services, operated by Flixbus USA, depart from Anaheim Regional Transportation Intermodal Center station.
Santa Ana to San Francisco bus services, operated by Flixbus USA, arrive at San Francisco station.
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The distance between Santa Ana and San Francisco is 607.6 km. The road distance is 665 km.
Flixbus USA operates a bus from Anaheim Regional Transportation Intermodal Center to San Francisco once daily. Tickets cost $65–100 and the journey takes 8h 15m.
