The average bus between Santa Ana and University of Southern California takes 2h 22m and the fastest bus takes 1h 45m. There is an hourly bus service from Santa Ana to University of Southern California. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run hourly between Santa Ana and University of Southern California. The earliest departure is at 4:54 AM at night, and the last departure from Santa Ana is at 11:25 PM which arrives into University of Southern California at 1:40 AM. All services require a transfer at Harbor-East Shuttle Area and take an average of 2h 22m. The schedules shown below are for the next available departures.

1h 54m • 1 change
Arrives next day

2h 19m • 1 change
Arrives next day

2h 15m • 1 change

2h 9m • 1 change

2h 6m • 1 change

2h 7m • 1 change

2h 44m • 1 change

2h 9m • 1 change

2h 6m • 1 change

2h 7m • 1 change

2h 44m • 1 change
Want to know about travelling from Santa Ana to University of Southern California? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Santa Ana to University of Southern California. However, there are services departing from Santa Ana station and arriving at University of Southern California station via Harbor Transitway / 37th St / USC. The journey, including transfers, takes approximately 2h 22m.
Santa Ana to University of Southern California bus services, operated by OCTA, depart from Disneyland Employee's Entrance station.
Santa Ana to University of Southern California bus services, operated by OCTA, arrive at Harbor Transitway / 37th St / USC station.
The distance between Santa Ana and University of Southern California is 49.2 km. The road distance is 78 km.
Metro Los Angeles operates a bus from Disneyland Employee's Entrance to Harbor Transitway / 37th St / USC every 30 minutes. Tickets cost $1–2 and the journey takes 1h 45m.