The average bus between Santa Clarita and Vacaville takes 23h 45m and the fastest bus takes 22h 33m. The bus service runs several times per day from Santa Clarita to Vacaville. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Santa Clarita and Vacaville. The earliest departure is at 6:40 AM in the morning, and the last departure from Santa Clarita is at 1:45 PM which arrives into Vacaville at 12:18 PM. All services require a transfer at Glendale and take an average of 23h 45m. The schedules shown below are for the next available departures.
Arrives next day




24h 8m • 4 changes
Arrives next day




22h 33m • 4 changes
Arrives next day




24h 8m • 4 changes
Arrives next day




22h 33m • 4 changes
Want to know about travelling from Santa Clarita to Vacaville? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Santa Clarita to Vacaville. However, there are services departing from Santa Clarita station and arriving at Vacaville station via Oakland. The journey, including transfers, takes approximately 23h 45m.
Santa Clarita to Vacaville bus services, operated by Amtrak, depart from Glendale Bus Stop station.
Santa Clarita to Vacaville bus services, operated by Amtrak, arrive at Vacaville Transportation Center station.
The distance between Santa Clarita and Vacaville is 538 km. The road distance is 751 km.
You can take a train from Newhall to Vacaville Transportation Center via Glendale, Glendale Bus Stop, Oakland, West Oakland, North Concord / Martinez, and North Concord Station in around 11h 32m.