Bus Santa Cruz to Milpitas from $22 | Tickets & Timetables

Santa Cruz to Milpitas buses

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Trip Overview

The average bus between Santa Cruz and Milpitas takes 2h 4m and the fastest bus takes 1h 39m. There is an hourly bus service from Santa Cruz to Milpitas. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

2h 4m
Duration: 40 mi
Distance: $22
Average price: Hourly
Frequency

Bus, line 66 bus

best

Take the bus from Front to Diridon Stationbus 17
Take the bus from 1st & Santa Clara to Main & Serrabus 66

1h 52m

$14–26

Santa Cruz to Milpitas bus times

Buses run hourly between Santa Cruz and Milpitas. The earliest departure is at 5:00 AM in the morning, and the last departure from Santa Cruz is at 10:30 PM which arrives into Milpitas at 12:37 AM. All services require a transfer at Diridon Station and take an average of 2h 4m. The schedules shown below are for the next available departures.

Departing Monday, August 17, 2026

10:50 AM → 12:58 PM
2h 8m • 2 changes
12:00 PM → 1:57 PM
1h 57m • 2 changes
12:45 PM → 2:59 PM
2h 14m • 2 changes
1:25 PM → 3:32 PM
2h 7m • 2 changes
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Departing Tuesday, August 18, 2026

5:00 AM → 6:48 AM
1h 48m • 2 changes
5:25 AM → 7:13 AM
1h 48m • 2 changes
5:40 AM → 7:28 AM
1h 48m • 2 changes
6:20 AM → 8:26 AM
2h 6m • 2 changes
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Departing Wednesday, August 19, 2026

5:00 AM → 6:48 AM
1h 48m • 2 changes
5:25 AM → 7:13 AM
1h 48m • 2 changes
5:40 AM → 7:28 AM
1h 48m • 2 changes
6:20 AM → 8:26 AM
2h 6m • 2 changes
Show more

Frequently asked questions

Want to know about travelling from Santa Cruz to Milpitas? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.