The average bus between Santa Cruz and Van Nuys takes 10h 41m and the fastest bus takes 8h 24m. The bus service runs several times per day from Santa Cruz to Van Nuys. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Santa Cruz and Van Nuys. The earliest departure is at 9:50 AM in the morning, and the last departure from Santa Cruz is at 10:30 PM which arrives into Van Nuys at 1:32 PM. All services require a transfer at Diridon Station and take an average of 10h 41m. The schedules shown below are for the next available departures.




8h 31m • 4 changes




9h 7m • 4 changes
Arrives next day




15h 12m • 4 changes




8h 24m • 4 changes




9h • 4 changes
Arrives next day




15h 2m • 4 changes




8h 24m • 4 changes




9h • 4 changes
Arrives next day




15h 2m • 4 changes




8h 24m • 4 changes




9h • 4 changes
Arrives next day




15h 2m • 4 changes
Want to know about travelling from Santa Cruz to Van Nuys? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Santa Cruz to Van Nuys. However, there are services departing from Santa Cruz station and arriving at Van Nuys station via Diridon Station station. The journey, including transfers, takes approximately 10h 41m.
Santa Cruz to Van Nuys bus services, operated by Santa Cruz Metro, depart from Front station.
Santa Cruz to Van Nuys bus services, operated by Santa Cruz Metro, arrive at Los Angeles - Pacoima station.
The distance between Santa Cruz and Van Nuys is 448.3 km. The road distance is 630 km.
You can take a bus from Front to Van Nuys / Victory via Diridon Station, San Jose Diridon, Santa Clara & 1st, King & Virginia, San Jose - King Rd Pink Elephant, Los Angeles - Pacoima, and Van Nuys / Laurel Canyon in around 9h 28m.