The average bus between Santa Fe and Seville takes 5h 3m and the fastest bus takes 3h 35m. The bus service runs several times per day from Santa Fe to Seville. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 4 hours between Santa Fe and Seville. The earliest departure is at 8:25 AM in the morning, and the last departure from Santa Fe is at 7:50 PM which arrives into Seville at 6:50 AM. All services require a transfer, and take on average 5h 3m. The schedules shown below are for the next available departures.

4h 5m • 1 change

3h 50m • 1 change
Arrives next day

11h • 1 change

4h 35m • 1 change

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3h 50m • 1 change

4h 35m • 1 change

4h 20m • 1 change

4h 5m • 1 change

3h 50m • 1 change

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4h 20m • 1 change

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4h 35m • 1 change

4h 20m • 1 change

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3h 50m • 1 change
Want to know about travelling from Santa Fe to Seville? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Santa Fe to Seville. However, there are services departing from Santa Fe station and arriving at Seville station via Sevilla, Estación de Autobuses (Plaza de Armas). The journey, including transfers, takes approximately 5h 3m.
Santa Fe to Seville bus services, operated by ALSA, depart from Granada Estación de Autobuses station.
Santa Fe to Seville bus services, operated by ALSA, arrive at Sevilla, Estación de Autobuses (Plaza de Armas) station.
Book your Santa Fe to Seville bus tickets online with ALSA.
The distance between Santa Fe and Seville is 200.6 km. The road distance is 253 km.
ALSA operates a bus from Granada Estación de Autobuses to Sevilla, Estación de Autobuses (Plaza de Armas) every 2 hours. Tickets cost €20–29 and the journey takes 3h.