The average bus between Santa Fe Depot and San Ysidro takes 1h 32m and the fastest bus takes 1h 16m. The bus runs at least 2 times per hour from Santa Fe Depot to San Ysidro. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 30 minutes between Santa Fe Depot and San Ysidro. The earliest departure is at 3:35 AM at night, and the last departure from Santa Fe Depot is at 11:31 PM which arrives into San Ysidro at 1:01 AM. All services require a transfer at 1st Av & Broadway and take an average of 1h 32m. The schedules shown below are for the next available departures.

1h 24m • 1 change
1h 35m • 1 change
1h 27m • 1 change
1h 34m • 1 change
1h 56m • 1 change
1h 20m • 1 change
1h 23m • 1 change
1h 33m • 1 change
2h 26m • 1 change
1h 23m • 1 change
1h 27m • 1 change
1h 30m • 1 change
2h 56m • 1 change
1h 27m • 1 change
1h 38m • 1 change
1h 16m • 1 change
1h 56m • 1 change
1h 20m • 1 change
1h 23m • 1 change
1h 33m • 1 change
1h 56m • 1 change
1h 20m • 1 change
1h 23m • 1 change
1h 33m • 1 change
1h 56m • 1 change
1h 20m • 1 change
1h 23m • 1 change
1h 33m • 1 changeWant to know about travelling from Santa Fe Depot to San Ysidro? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Santa Fe Depot to San Ysidro. However, there are services departing from 1st Av & Broadway station and arriving at Iris Avenue Transit Center station via Iris Avenue Transit Center station. The journey, including transfers, takes approximately 1h 32m.
Santa Fe Depot to San Ysidro bus services, operated by San Diego Metro Transit, depart from 1st Av & Broadway station.
Santa Fe Depot to San Ysidro bus services, operated by San Diego Metro Transit, arrive at Iris Avenue Transit Center station.
The distance between Santa Fe Depot and San Ysidro is 21.8 km. The road distance is 24 km.
San Diego Metro Transit operates a bus from 1st Av & Broadway to Iris Avenue Transit Center every 30 minutes. Tickets cost $2–5 and the journey takes 1h 6m.