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Santa Fe Depot to Santa Ana buses

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Trip Overview

The bus between Santa Fe Depot and Santa Ana takes 2h 5m. There is at least one bus per day from Santa Fe Depot to Santa Ana. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

2h 5m
Duration
92 mi
Distance
Once daily
Frequency

Santa Fe Depot to Santa Ana bus times

Buses run once daily between Santa Fe Depot and Santa Ana. The service departs Santa Fe Depot at 10:10 PM at night, which arrives into Santa Ana at 00:15:00. All services run direct with no transfers required, and take on average 2h 5m. The schedules shown below are for the next available departures.

Departing Monday, November 2, 2026

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    Arrives next day

    bus bus 2h 5m • Direct

Departing Tuesday, November 3, 2026

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    Arrives next day

    bus bus 2h 5m • Direct

Departing Wednesday, November 4, 2026

  •  → 

    Arrives next day

    bus bus 2h 5m • Direct

Departing Thursday, November 5, 2026

  •  → 

    Arrives next day

    bus bus 2h 5m • Direct

Departing Friday, November 6, 2026

  •  → 

    Arrives next day

    bus bus 2h 5m • Direct

Departing Saturday, November 7, 2026

  •  → 

    Arrives next day

    bus bus 2h 5m • Direct

Frequently asked questions

Want to know about travelling from Santa Fe Depot to Santa Ana? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Santa Fe Depot to Santa Ana.ExpandLaunch map view
  • Distance: 92 mi
  • Duration: 2h 5m

What companies run services between Santa Fe Depot, San Diego County, CA, USA and Santa Ana, CA, USA?

Amtrak operates a bus from San Diego to Santa Ana once daily, and the journey takes 2h 5m.

Operators