Rome2Rio

Santa Maria Novella to Colosseum buses

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Trip Overview

The average bus between Santa Maria Novella and Colosseum takes 21h 50m and the fastest bus takes 21h 30m. The bus runs, on average, 6 times per week from Santa Maria Novella to Colosseum. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

21h 50m
Duration
281 km
Distance
€32
Average price
6 times a week
Frequency

Santa Maria Novella to Colosseum bus times

Buses run 6 times a week between Santa Maria Novella and Colosseum. The service departs Santa Maria Novella at 2:45 AM at night, which arrives into Colosseum at 00:15:58. All services require a transfer at Florence and take an average of 21h 50m. The schedules shown below are for the next available departures.

Departing Sunday, November 8, 2026

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    Arrives next day

    FlixBusATAC S.p.A. Azienda per la mobilità21h 30m • 1 change

Departing Monday, November 9, 2026

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    Arrives next day

    FlixBusATAC S.p.A. Azienda per la mobilità21h 31m • 1 change

Departing Tuesday, November 10, 2026

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    Arrives next day

    FlixBusATAC S.p.A. Azienda per la mobilità21h 31m • 1 change

Departing Wednesday, November 11, 2026

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    Arrives next day

    FlixBusATAC S.p.A. Azienda per la mobilità21h 31m • 1 change

Departing Thursday, November 12, 2026

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    Arrives next day

    FlixBusATAC S.p.A. Azienda per la mobilità21h 31m • 1 change

Departing Friday, November 13, 2026

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    Arrives next day

    FlixBusATAC S.p.A. Azienda per la mobilità23h 26m • 1 change

Frequently asked questions

Want to know about travelling from Santa Maria Novella to Colosseum? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Santa Maria Novella to Colosseum.ExpandLaunch map view
  • Distance: 281.5 km
  • Duration: 21h 50m

What companies run services between Santa Maria Novella, Italy and Colosseum, Italy?

FlixBus operates a bus from Florence to Roma, Autostazione Tiburtina twice daily. Tickets cost €24–40 and the journey takes 3h 25m. TTI Leonettibus SRL also services this route once a week.

Operators